Tumor Necrosis Factor (TNF) Antibody

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Catalogue No: abx027445
Price: US$290.00
(Size: 80 µl)

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Datasheet SDS
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Target Tumor Necrosis Factor (TNF)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01375 (UniProt, ExPASy)
UniProt Secondary AC O43647, Q9P1Q2, Q9UIV3
UniProt Entry Name TNFA_HUMAN
Gene Symbol TNF
GeneID 7124
OMIM 191160
HGNC 11892
KEGG hsa:7124
Ensembl ENSG00000232810
String 9606.ENSP00000398698
Molecular Weight Calculated MW: 25.6 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor (TNF)


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