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Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) Antibody
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Catalogue No: abx001148
Price:
US$217.50
(Size: 20 µl)
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TNFRSF10B Antibody is a Rabbit Polyclonal antibody against TNFRSF10B. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 260-440 of human DR5/TRAILR2/TNFRSF10B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14763 (UniProt, ExPASy) |
| UniProt Secondary AC | O14720, O15508, O15517, O15531, Q6UXM8, Q7Z360, Q9BVE0 |
| UniProt Entry Name | TR10B_HUMAN |
| Gene Symbol | TNFRSF10B |
| GeneID | 8795 |
| NCBI Accession | NP_003833.4 |
| KEGG | hsa:8795 |
| String | 9606.ENSP00000276431 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |