Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14) Antibody

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Catalogue No: abx001604
Price: US$217.50
(Size: 20 µl)
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Western blot analysis of lysates from Raji cells, using HVEM/TNFRSF14 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14) Antibody

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Datasheet SDS
TNFRSF14 Antibody is a Rabbit Polyclonal antibody against TNFRSF14. The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.

Target Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 39-202 of human HVEM/TNFRSF14.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92956 (UniProt, ExPASy)
UniProt Secondary AC B3KW30, B9DI89, Q6IB95, Q8N634, Q8WXR1, Q96J31, Q9UM65
UniProt Entry Name TNR14_HUMAN
Gene Symbol TNFRSF14
GeneID 8764
NCBI Accession NP_003811.2
KEGG hsa:8764
String 9606.ENSP00000347948
Molecular Weight Calculated MW: 30 kDa
Observed MW: 30 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14)
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