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Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) Antibody
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Catalogue No: abx001016
Price:
US$217.50
(Size: 20 µl)
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TNFRSF1B Antibody is a Rabbit Polyclonal antibody against TNFRSF1B. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 295-377 of human TNFR2/TNFRSF1B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20333 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AJZ3, Q16042, Q6YI29, Q9UIH1 |
| Gene Symbol | TNFRSF1B |
| GeneID | 7133 |
| NCBI Accession | NP_001057.1 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |