Tumor Necrosis Factor Ligand Superfamily Member 12 (TNFSF12) Antibody

TNFSF12 Antibody is a Rabbit Polyclonal antibody against TNFSF12. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants.

Target	Tumor Necrosis Factor Ligand Superfamily Member 12 (TNFSF12)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43508 (UniProt, ExPASy)
UniProt Secondary AC	Q8IZK7, Q8WUZ7
UniProt Entry Name	TNF12_HUMAN
Gene Symbol	TNFSF12
GeneID	8742
NCBI Accession	NP_003800.1
KEGG	hsa:407977 hsa:8742
String	9606.ENSP00000293825
Molecular Weight	Calculated MW: 27 kDa Observed MW: 27 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	1.80 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Ligand Superfamily Member 12 (TNFSF12)

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