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Cardiac Troponin T2 (TNNT2) Antibody
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Catalogue No: abx001040
Price:
US$203.00
(Size: 20 µl)
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Cardiac Troponin T2 (TNNT2) Antibody is a Rabbit Polyclonal antibody against Cardiac Troponin T2 (TNNT2). The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Research Articles on Cardiac Troponin T2 (TNNT2)
| Target | Cardiac Troponin T2 (TNNT2) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/5000, IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Cardiac troponin T (TNNT2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P45379 (UniProt, ExPASy) |
| UniProt Secondary AC | A2TDB9, A8K3K6, O60214, Q99596, Q99597, Q9BUF6, Q9UM96 |
| UniProt Entry Name | TNNT2_HUMAN |
| Gene Symbol | TNNT2 |
| GeneID | 7139 |
| OMIM | 115195 |
| NCBI Accession | NP_001001432.1 NM_001001432.2 |
| HGNC | 11949 |
| Ensembl | ENSG00000118194 |
| String | 9606.ENSP00000236918 |
| Molecular Weight | Calculated MW: 36 kDa Observed MW: 42 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |