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Toll Like Receptor 4 (TLR4) Antibody
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Catalogue No: abx239893
Price:
US$406.00
(Size: 100 µg)
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Toll Like Receptor 4 (TLR4) Antibody is a Mouse Monoclonal antibody for the detection of TLR4. TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Research Articles on Toll Like Receptor 4 (TLR4)
| Target | Toll Like Receptor 4 (TLR4) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/8000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | toll-like receptor 4 |
| Isotype | IgG2b |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O00206 (UniProt, ExPASy) |
| Gene Symbol | TLR4 |
| GeneID | 7099 |
| OMIM | 603030 |
| HGNC | 11850 |
| Ensembl | ENSG00000136869 |
| Molecular Weight | Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |