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Toll-Like Receptor 5 (TLR5) Antibody
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Catalogue No: abx001438
Price:
US$348.00
(Size: 60 µl)
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TLR5 Antibody is a Rabbit Polyclonal antibody against TLR5. This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009].
Research Articles on Toll-Like Receptor 5 (TLR5)
| Target | Toll-Like Receptor 5 (TLR5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TLR5 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60602 (UniProt, ExPASy) |
| UniProt Entry Name | TLR5_HUMAN |
| Gene Symbol | TLR5 |
| GeneID | 7100 |
| NCBI Accession | NP_003259.2 |
| KEGG | hsa:7100 |
| String | 9606.ENSP00000440643 |
| Molecular Weight | Calculated MW: 97 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
