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Toll Like Receptor 8 (TLR8) Antibody
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Catalogue No: abx149074
Price:
US$406.00
(Size: 100 µg)
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Toll Like Receptor 8 (TLR8) Antibody is a Rabbit Polyclonal antibody for the detection of TLR8. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Research Articles on Toll Like Receptor 8 (TLR8)
| Target | Toll Like Receptor 8 (TLR8) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Toll-like receptor 8 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9NR97 (UniProt, ExPASy) |
| UniProt Secondary AC | B3Y654, D1CS70, D1CS76, Q495P4, Q6UXL6, Q9NYG9 |
| UniProt Entry Name | TLR8_HUMAN |
| Gene Symbol | TLR8 |
| GeneID | 51311 |
| OMIM | 300366 |
| NCBI Accession | NP_057694.2 |
| HGNC | 15632 |
| Ensembl | ENST00000218032, ENSP00000218032, ENSG00000101916 [Q9NR97-1], ENST00000311912, ENSP00000312082, ENSG00000101916 [Q9NR97-2] |
| String | 9606.ENSP00000312082 |
| Molecular Weight | Observed MW: 120 kDa, 55 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |