Toll Like Receptor 8 (TLR8) Antibody

Toll Like Receptor 8 (TLR8) Antibody is a Rabbit Polyclonal antibody for the detection of TLR8.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Target	Toll Like Receptor 8 (TLR8)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Toll-like receptor 8
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9NR97 (UniProt, ExPASy)
UniProt Secondary AC	B3Y654, D1CS70, D1CS76, Q495P4, Q6UXL6, Q9NYG9
UniProt Entry Name	TLR8_HUMAN
Gene Symbol	TLR8
GeneID	51311
OMIM	300366
NCBI Accession	NP_057694.2
HGNC	15632
Ensembl	ENST00000218032, ENSP00000218032, ENSG00000101916 [Q9NR97-1], ENST00000311912, ENSP00000312082, ENSG00000101916 [Q9NR97-2]
String	9606.ENSP00000312082
Molecular Weight	Observed MW: 120 kDa, 55 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Toll Like Receptor 8 (TLR8)

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