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Topoisomerase III Beta (TOP3B) Antibody
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Catalogue No: abx029055
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.
Research Articles on Topoisomerase III Beta (TOP3B)
| Target | Topoisomerase III Beta (TOP3B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95985 (UniProt, ExPASy) |
| UniProt Secondary AC | A0M8Q3, Q9BUP5 |
| UniProt Entry Name | TOP3B_HUMAN |
| Gene Symbol | TOP3B |
| KEGG | hsa:8940 |
| String | 9606.ENSP00000381773 |
| Molecular Weight | Calculated MW: 96.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |