Tissue-Type Plasminogen Activator (PLAT) Antibody

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Catalogue No: abx032978
Price: US$326.25
(Size: 80 µl)
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Tissue-Type Plasminogen Activator (PLAT) Antibody
Tissue-Type Plasminogen Activator (PLAT) Antibody Tissue-Type Plasminogen Activator (PLAT) Antibody Tissue-Type Plasminogen Activator (PLAT) Antibody

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Datasheet SDS
TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.

Target Tissue-Type Plasminogen Activator (PLAT)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 371-399 amino acids from the Central region of human TPA.
Isotype IgG
Form Liquid
Purification Purified Rabbit Polyclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00750 (UniProt, ExPASy)
UniProt Entry Name TPA_HUMAN
KEGG hsa:5327
String 9606.ENSP00000220809
Molecular Weight Calculated MW: 62.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Tissue-Type Plasminogen Activator (PLAT)
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