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Tropomyosin Alpha-4 Chain (TPM4) Antibody
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Catalogue No: abx027000
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Tropomyosin Alpha-4 Chain (TPM4)
| Target | Tropomyosin Alpha-4 Chain (TPM4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TPM4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P67936 (UniProt, ExPASy) |
| UniProt Entry Name | TPM4_HUMAN |
| KEGG | hsa:7171 |
| Molecular Weight | Calculated MW: 28.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig and Horse TPM4. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |