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Tripeptidyl Peptidase I (TPP1) Antibody
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Catalogue No: abx004302
Price:
US$217.50
(Size: 20 µl)
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TPP1 Antibody is a Rabbit Polyclonal antibody against TPP1. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Research Articles on Tripeptidyl Peptidase I (TPP1)
| Target | Tripeptidyl Peptidase I (TPP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human TPP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14773 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53HT1, Q5JAK6, Q6UX56, Q71JP6, Q96C37 |
| UniProt Entry Name | TPP1_HUMAN |
| Gene Symbol | TPP1 |
| GeneID | 1200 |
| NCBI Accession | NP_000382.3 |
| KEGG | hsa:1200 |
| String | 9606.ENSP00000299427 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |