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Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) Antibody
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Catalogue No: abx026532
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].
Research Articles on Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD)
| Target | Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 126-151 amino acids from the Central region of human TRADD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15628 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDS3, B3KQZ9, Q52NZ1 |
| UniProt Entry Name | TRADD_HUMAN |
| KEGG | hsa:8717 |
| String | 9606.ENSP00000341268 |
| Molecular Weight | Calculated MW: 34.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |