+44 (0) 1223 755950
+1 832 327 7413
Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) Antibody
REQUEST MORE INFO
Catalogue No: abx001059
Price:
US$348.00
(Size: 60 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
TRADD Antibody is a Rabbit Polyclonal antibody against TRADD. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Research Articles on Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD)
| Target | Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TRADD |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15628 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDS3, B3KQZ9, Q52NZ1 |
| UniProt Entry Name | TRADD_HUMAN |
| Gene Symbol | TRADD |
| GeneID | 8717 |
| NCBI Accession | NP_003780.1 |
| KEGG | hsa:8717 |
| String | 9606.ENSP00000341268 |
| Molecular Weight | Calculated MW: 27 kDa/34 kDa Observed MW: 32 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |