TNF Receptor-Associated Factor 4 (TRAF4) Antibody

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P) H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

Target	TNF Receptor-Associated Factor 4 (TRAF4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 427-455 amino acids from the C-terminal region of human TRAF4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BUZ4 (UniProt, ExPASy)
UniProt Secondary AC	O75615, Q14848, Q2KJU4, Q2PJN8
UniProt Entry Name	TRAF4_HUMAN
Gene Symbol	TRAF4
String	9606.ENSP00000262395
Molecular Weight	Calculated MW: 53.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse TRAF4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on TNF Receptor-Associated Factor 4 (TRAF4)

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