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Transcription Activator BRG1 (BRG1) Antibody
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Catalogue No: abx020073
Price:
US$406.00
(Size: 100 µg)
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Transcription Activator BRG1 (BRG1) Antibody is a Rabbit Polyclonal antibody for the detection of SMARCA4. SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Research Articles on Transcription Activator BRG1 (BRG1)
| Target | Transcription Activator BRG1 (BRG1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P51532 (UniProt, ExPASy) |
| UniProt Secondary AC | B1A8Z4, B1A8Z5, B1A8Z6, B1A8Z7, E9PBR8, O95052, Q9HBD3 |
| UniProt Entry Name | SMCA4_HUMAN |
| Gene Symbol | SMARCA4 |
| GeneID | 6597 |
| OMIM | 603254 |
| HGNC | 11100 |
| KEGG | hsa:6597 |
| Ensembl | ENSG00000127616 |
| String | 9606.ENSP00000395654 |
| Molecular Weight | Observed MW: 185 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |