Transcription Factor SP1 (SP1) Antibody

Transcription Factor SP1 (SP1) Antibody is a Rabbit Polyclonal antibody for the detection of SP1.

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Target	Transcription Factor SP1 (SP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Transcription factor Sp1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P08047 (UniProt, ExPASy)
UniProt Secondary AC	E4Z9M7, G5E9M8, Q86TN8, Q9H3Q5, Q9NR51, Q9NY21, Q9NYE7
UniProt Entry Name	SP1_HUMAN
Gene Symbol	SP1
GeneID	6667
OMIM	189906
HGNC	11205
KEGG	hsa:6667
Ensembl	ENSG00000185591
String	9606.ENSP00000329357
Molecular Weight	Observed MW: 90 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Transcription Factor SP1 (SP1)

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