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Transglutaminase Antibody
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Catalogue No: abx033705
Price:
US$326.25
(Size: 80 µl)
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Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Research Articles on Transglutaminase
| Target | Transglutaminase |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 413-442 amino acids from the Central region of human Transglutaminase (TGM2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P21980 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5V9, Q16436, Q6B838, Q9BTN7, Q9H035, Q9UH35 |
| UniProt Entry Name | TGM2_HUMAN |
| KEGG | hsa:7052 |
| String | 9606.ENSP00000355330 |
| Molecular Weight | Calculated MW: 77.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |