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Tripartite Motif-Containing Protein 5 (TRIM5) Antibody
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Catalogue No: abx026418
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Articles on Tripartite Motif-Containing Protein 5 (TRIM5)
| Target | Tripartite Motif-Containing Protein 5 (TRIM5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of human TRIM5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9C035 (UniProt, ExPASy) |
| UniProt Entry Name | TRIM5_HUMAN |
| Gene Symbol | TRIM5 |
| String | 9606.ENSP00000369373 |
| Molecular Weight | Calculated MW: 56.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |