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High Affinity Nerve Growth Factor Receptor (NTRK1) Antibody
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Catalogue No: abx033615
Price:
US$326.25
(Size: 80 µl)
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TRKA (also known as NTRK1) is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Research Articles on High Affinity Nerve Growth Factor Receptor (NTRK1)
| Target | High Affinity Nerve Growth Factor Receptor (NTRK1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 654-683 amino acids from the Central region of human TRKA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04629 (UniProt, ExPASy) |
| UniProt Entry Name | NTRK1_HUMAN |
| KEGG | hsa:4914 |
| String | 9606.ENSP00000431418 |
| Molecular Weight | Calculated MW: 87.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Chicken NTRK1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |