High Affinity Nerve Growth Factor Receptor (NTRK1) Antibody

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Catalogue No: abx033615
Price: US$326.25
(Size: 80 µl)

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High Affinity Nerve Growth Factor Receptor (NTRK1) Antibody High Affinity Nerve Growth Factor Receptor (NTRK1) Antibody

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Datasheet SDS
TRKA (also known as NTRK1) is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Target High Affinity Nerve Growth Factor Receptor (NTRK1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 654-683 amino acids from the Central region of human TRKA.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04629 (UniProt, ExPASy)
UniProt Entry Name NTRK1_HUMAN
KEGG hsa:4914
String 9606.ENSP00000431418
Molecular Weight Calculated MW: 87.5 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat and Chicken NTRK1.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on High Affinity Nerve Growth Factor Receptor (NTRK1)
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