+44 (0) 1223 755950
+1 832 327 7413
Tumor-Associated Calcium Signal Transducer 2 (TROP2) Antibody
REQUEST MORE INFO
Catalogue No: abx032931
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Research Articles on Tumor-Associated Calcium Signal Transducer 2 (TROP2)
| Target | Tumor-Associated Calcium Signal Transducer 2 (TROP2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 162-190 amino acids from the Central region of human TROP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purifed by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09758 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15658, Q6FG48, Q7Z7Q4, Q96QD2 |
| UniProt Entry Name | TACD2_HUMAN |
| KEGG | hsa:4070 |
| String | 9606.ENSP00000360269 |
| Molecular Weight | Calculated MW: 35.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |