Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7) Antibody

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Catalogue No: abx025139
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM].

Target Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1).
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96QT4 (UniProt, ExPASy)
UniProt Secondary AC Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2
UniProt Entry Name TRPM7_HUMAN
NCBI Accession NP_060142.3
KEGG hsa:54822
String 9606.ENSP00000320239
Molecular Weight Calculated MW: 213 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat TRPM7.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7)
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