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Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7) Antibody
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Catalogue No: abx025139
Price:
US$326.25
(Size: 80 µl)
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TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM].
Research Articles on Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7)
| Target | Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96QT4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2 |
| UniProt Entry Name | TRPM7_HUMAN |
| NCBI Accession | NP_060142.3 |
| KEGG | hsa:54822 |
| String | 9606.ENSP00000320239 |
| Molecular Weight | Calculated MW: 213 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat TRPM7. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |