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Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Antibody
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Catalogue No: abx027725
Price:
US$326.25
(Size: 80 µl)
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Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Research Articles on Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)
| Target | Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 124-153 amino acids from the N-terminal region of human TRPV1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NER1 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RUA9, Q3LU47, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22 |
| UniProt Entry Name | TRPV1_HUMAN |
| Gene Symbol | TRPV1 |
| KEGG | hsa:7442 |
| String | 9606.ENSP00000461007 |
| Molecular Weight | Calculated MW: 95 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |