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TSC2 (pS1388) Antibody
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Catalogue No: abx032288
Price:
US$326.25
(Size: 80 µl)
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Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on TSC2 (pS1388)
| Target | TSC2 (pS1388) |
| Clonality | Polyclonal |
| Target Modification | Ser1388 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1388 of human TSC2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49815 (UniProt, ExPASy) |
| UniProt Entry Name | TSC2_HUMAN |
| KEGG | hsa:7249 |
| String | 9606.ENSP00000219476 |
| Molecular Weight | Calculated MW: 201 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat TSC2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |