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Tumor Susceptibility Gene 101 (TSG101) Antibody
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Catalogue No: abx001823
Price:
US$203.00
(Size: 20 µl)
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TSG101 Antibody is a Rabbit Polyclonal antibody against TSG101. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008].
Research Articles on Tumor Susceptibility Gene 101 (TSG101)
| Target | Tumor Susceptibility Gene 101 (TSG101) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50-1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 291-390 of human TSG101/VPS23. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99816 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9BUM5 |
| UniProt Entry Name | TS101_HUMAN |
| Gene Symbol | TSG101 |
| GeneID | 7251 |
| NCBI Accession | NP_006283.1 |
| KEGG | hsa:7251 |
| String | 9606.ENSP00000251968 |
| Molecular Weight | Calculated MW: 44 kDa Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |