Thyrotropin Subunit Beta (TSHB) Antibody

TSHB Antibody is a Rabbit Polyclonal antibody against TSHB. The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Target	Thyrotropin Subunit Beta (TSHB)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-138 of human TSHB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01222 (UniProt, ExPASy)
UniProt Secondary AC	B1AKP0, Q16163
UniProt Entry Name	TSHB_HUMAN
Gene Symbol	TSHB
GeneID	7252
NCBI Accession	NP_000540.2
KEGG	hsa:7252
String	9606.ENSP00000256592
Molecular Weight	Calculated MW: 16 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1.33 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Thyrotropin Subunit Beta (TSHB)

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