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Thyrotropin Receptor (TSHR) Antibody
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Catalogue No: abx005203
Price:
US$203.00
(Size: 20 µl)
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TSHR Antibody is a Rabbit Polyclonal antibody against TSHR. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Research Articles on Thyrotropin Receptor (TSHR)
| Target | Thyrotropin Receptor (TSHR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16473 (UniProt, ExPASy) |
| UniProt Entry Name | TSHR_HUMAN |
| Gene Symbol | TSHR |
| GeneID | 7253 |
| NCBI Accession | NP_001018046.1 |
| KEGG | hsa:7253 |
| String | 9606.ENSP00000441235 |
| Molecular Weight | Calculated MW: 87 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.17 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |