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Tumor Protein P63 (TP63) Antibody
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Catalogue No: abx011310
Price:
US$406.00
(Size: 100 µg)
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Tumor Protein P63 (TP63) Antibody is a Rabbit Polyclonal antibody for the detection of p63. TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd (P40), 50kd (P60),63kd (P63) and 73kd (P73L). It is Nuclear stain.
Research Articles on Tumor Protein P63 (TP63)
| Target | Tumor Protein P63 (TP63) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | tumor protein p63 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9H3D4 (UniProt, ExPASy) |
| Gene Symbol | TP63 |
| GeneID | 8626 |
| OMIM | 103285 |
| HGNC | 15979 |
| Ensembl | ENSG00000073282 |
| Molecular Weight | Observed MW: 45-75 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |