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Tyrosine Kinase 2 (TYK2) Antibody
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Catalogue No: abx001740
Price:
US$348.00
(Size: 60 µl)
Click on the image to see the image legend
TYK2 Antibody is a Rabbit Polyclonal antibody against TYK2. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Research Articles on Tyrosine Kinase 2 (TYK2)
| Target | Tyrosine Kinase 2 (TYK2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TYK2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P29597 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6QB10, Q96CH0 |
| UniProt Entry Name | TYK2_HUMAN |
| Gene Symbol | TYK2 |
| GeneID | 7297 |
| NCBI Accession | NP_003322.3 |
| KEGG | hsa:7297 |
| String | 9606.ENSP00000431885 |
| Molecular Weight | Calculated MW: 133 kDa Observed MW: 134 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
