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Tyrosine Kinase 2 (TYK2) Antibody
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Catalogue No: abx117217
Price:
US$522.00
(Size: 100 µl)
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TYK2 Antibody is a Rabbit Polyclonal antibody against TYK2. Tyk2, a member of the Jak family of protein tyrosine kinases, associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and interferon-alpha and betaFollowing ligand binding, Tyk2 is activated by phosphorylation on Tyr1054 and/or Tyr1055Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-beta signaling cascade.
Research Articles on Tyrosine Kinase 2 (TYK2)
| Target | Tyrosine Kinase 2 (TYK2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TYK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P29597 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6QB10, Q96CH0 |
| UniProt Entry Name | TYK2_HUMAN |
| Gene Symbol | TYK2 |
| GeneID | 7297 |
| KEGG | hsa:7297 |
| String | 9606.ENSP00000431885 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |