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Tyrosinase (TYR) Antibody
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Catalogue No: abx033344
Price:
US$290.00
(Size: 80 µl)
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TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation.
Research Articles on Tyrosinase (TYR)
| Target | Tyrosinase (TYR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 176-205 amino acids from the Central region of human TYR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14679 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1 |
| UniProt Entry Name | TYRO_HUMAN |
| Gene Symbol | TYR |
| KEGG | hsa:7299 |
| String | 9606.ENSP00000263321 |
| Molecular Weight | Calculated MW: 60.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse TYR. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |