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Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) Antibody
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Catalogue No: abx002379
Price:
US$348.00
(Size: 60 µl)
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TIE1 Antibody is a Rabbit Polyclonal antibody against TIE1. This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Articles on Tyrosine-Protein Kinase Receptor Tie-1 (TIE1)
| Target | Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TIE1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35590 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A949, B5A950 |
| UniProt Entry Name | TIE1_HUMAN |
| GeneID | 7075 |
| NCBI Accession | NP_005415.1 |
| KEGG | hsa:7075 |
| String | 9606.ENSP00000361554 |
| Molecular Weight | Calculated MW: 34 kDa/40 kDa/125 kDa Observed MW: 135/140 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
