+44 (0) 1223 755950
+1 832 327 7413
Tyrosine-tRNA Ligase, Cytoplasmic (YARS1) Antibody
REQUEST MORE INFO
Catalogue No: abx033490
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Research Articles on Tyrosine-tRNA Ligase, Cytoplasmic (YARS1)
| Target | Tyrosine-tRNA Ligase, Cytoplasmic (YARS1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human Tyrosyl tRNA synthetase (YARS). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54577 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KWK4, D3DPQ4, O43276, Q53EN1 |
| UniProt Entry Name | SYYC_HUMAN |
| Gene Symbol | YARS1 |
| GeneID | 8565 |
| OMIM | 603623 |
| HGNC | 12840 |
| KEGG | hsa:8565 |
| String | 9606.ENSP00000362576 |
| Molecular Weight | Calculated MW: 59.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |