Thymidylate Synthase (TYMS) Antibody

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Catalogue No: abx032932
Price: US$326.25
(Size: 80 µl)
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Thymidylate Synthase (TYMS) Antibody
Thymidylate Synthase (TYMS) Antibody Thymidylate Synthase (TYMS) Antibody Thymidylate Synthase (TYMS) Antibody

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Datasheet SDS
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.

Target Thymidylate Synthase (TYMS)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
Isotype IgG
Form Liquid
Purification Purified Rabbit Polyclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04818 (UniProt, ExPASy)
UniProt Secondary AC Q8WYK3, Q8WYK4
UniProt Entry Name TYSY_HUMAN
Gene Symbol TYMS
NCBI Accession NP_001062.1
KEGG hsa:7298
String 9606.ENSP00000315644
Molecular Weight Calculated MW: 35.7 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Thymidylate Synthase (TYMS)
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