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Splicing Factor U2AF 35 kDa Subunit (U2AF1) Antibody
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Catalogue No: abx000973
Price:
US$348.00
(Size: 60 µl)
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U2AF1 Antibody is a Rabbit Polyclonal antibody against U2AF1. U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
Research Articles on Splicing Factor U2AF 35 kDa Subunit (U2AF1)
| Target | Splicing Factor U2AF 35 kDa Subunit (U2AF1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human U2AF1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01081 (UniProt, ExPASy) |
| UniProt Secondary AC | Q701P4, Q71RF1 |
| UniProt Entry Name | U2AF1_HUMAN |
| Gene Symbol | U2AF1 |
| GeneID | 7307 |
| NCBI Accession | NP_006749.1 |
| KEGG | hsa:102724594 hsa:7307 |
| String | 9606.ENSP00000485022 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
