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Ubiquitin Conjugating Enzyme E2C (UBE2C) Antibody
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Catalogue No: abx004214
Price:
US$203.00
(Size: 20 µl)
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UBE2C Antibody is a Rabbit Polyclonal antibody against UBE2C. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
Research Articles on Ubiquitin Conjugating Enzyme E2C (UBE2C)
| Target | Ubiquitin Conjugating Enzyme E2C (UBE2C) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00762 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NP33, E1P5N7, G3XAB7 |
| UniProt Entry Name | UBE2C_HUMAN |
| Gene Symbol | UBE2C |
| GeneID | 11065 |
| NCBI Accession | NP_008950.1 |
| KEGG | hsa:11065 |
| String | 9606.ENSP00000348838 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 21 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |