Ubiquitin Specific Peptidase 7 (USP7) Antibody

Ubiquitin Specific Peptidase 7 (USP7) Antibody is a Rabbit Polyclonal antibody for the detection of USP7.

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

Target	Ubiquitin Specific Peptidase 7 (USP7)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	ubiquitin specific peptidase 7
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q93009 (UniProt, ExPASy)
UniProt Secondary AC	A6NMY8, B7Z815, H0Y3G8
UniProt Entry Name	UBP7_HUMAN
Gene Symbol	USP7
GeneID	7874
OMIM	602519
HGNC	12630
KEGG	hsa:7874
Ensembl	ENSG00000187555
String	9606.ENSP00000343535
Molecular Weight	Observed MW: 130 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin Specific Peptidase 7 (USP7)

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