Ubiquitin Recognition Factor In ER-Associated Degradation Protein 1 (UFD1L) Antibody

UFD1L Antibody is a Rabbit Polyclonal antibody against UFD1L. The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Target	Ubiquitin Recognition Factor In ER-Associated Degradation Protein 1 (UFD1L)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human UFD1L.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92890 (UniProt, ExPASy)
UniProt Secondary AC	A8MW31, Q9Y5N0
UniProt Entry Name	UFD1_HUMAN
Gene Symbol	UFD1
GeneID	7353
NCBI Accession	NP_005650.2
KEGG	hsa:7353
String	9606.ENSP00000263202
Molecular Weight	Calculated MW: 35 kDa Observed MW: 38 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin Recognition Factor In ER-Associated Degradation Protein 1 (UFD1L)

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