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UDP Glucuronosyltransferase Family 1 Member A4 (UGT1A4) Antibody
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Catalogue No: abx004248
Price:
US$348.00
(Size: 60 µl)
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UGT1A4 Antibody is a Rabbit Polyclonal antibody against UGT1A4. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Research Articles on UDP Glucuronosyltransferase Family 1 Member A4 (UGT1A4)
| Target | UDP Glucuronosyltransferase Family 1 Member A4 (UGT1A4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human UGT1A4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P22310 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R937, B8K288, Q5DT00 |
| UniProt Entry Name | UD14_HUMAN |
| Gene Symbol | UGT1A4 |
| GeneID | 54657 |
| NCBI Accession | NP_009051.1 |
| KEGG | hsa:54657 |
| String | 9606.ENSP00000362508 |
| Molecular Weight | Calculated MW: 49 kDa/60 kDa Observed MW: 69 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
