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Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody
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Catalogue No: abx034132
Price:
US$326.25
(Size: 80 µl)
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UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
Research Articles on Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1)
| Target | Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 229-257 amino acids from the Central region of human UHRF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96T88 (UniProt, ExPASy) |
| UniProt Entry Name | UHRF1_HUMAN |
| Gene Symbol | UHRF1 |
| NCBI Accession | NP_001041666.1 NP_037414.3 |
| KEGG | hsa:29128 |
| String | 9606.ENSP00000479617 |
| Molecular Weight | Calculated MW: 89.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |