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Uridine 5'-Monophosphate Synthase (UMPS) Antibody
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Catalogue No: abx004209
Price:
US$203.00
(Size: 20 µl)
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UMPS Antibody is a Rabbit Polyclonal antibody against UMPS. This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Research Articles on Uridine 5'-Monophosphate Synthase (UMPS)
| Target | Uridine 5'-Monophosphate Synthase (UMPS) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human UMPS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11172 (UniProt, ExPASy) |
| UniProt Entry Name | UMPS_HUMAN |
| Gene Symbol | UMPS |
| GeneID | 7372 |
| NCBI Accession | NP_000364.1 |
| KEGG | hsa:7372 |
| String | 9606.ENSP00000232607 |
| Molecular Weight | Calculated MW: 52 kDa Observed MW: 56 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |