Protein Unc-13 Homolog B (UNC13B) Antibody

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Catalogue No: abx027219
Price: US$326.25
(Size: 80 µl)
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Protein Unc-13 Homolog B (UNC13B) Antibody
Protein Unc-13 Homolog B (UNC13B) Antibody

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Datasheet SDS
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].

Target Protein Unc-13 Homolog B (UNC13B)
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human UNC13B.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14795 (UniProt, ExPASy)
UniProt Secondary AC Q2NKJ5, Q5VYM8
UniProt Entry Name UN13B_HUMAN
Gene Symbol UNC13B
KEGG hsa:10497
String 9606.ENSP00000367756
Molecular Weight Calculated MW: 181 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protein Unc-13 Homolog B (UNC13B)
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