Netrin Receptor UNC5C (UNC5C) Antibody

UNC5C belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) like domains and 2 type I thrombospondin motifs in the extracellular region.

Target	Netrin Receptor UNC5C (UNC5C)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 188-217 amino acids from the Central region of human UNC5C.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95185 (UniProt, ExPASy)
UniProt Secondary AC	Q8IUT0
UniProt Entry Name	UNC5C_HUMAN
Gene Symbol	UNC5C
KEGG	hsa:8633
String	9606.ENSP00000406022
Molecular Weight	Calculated MW: 103 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat UNC5C.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Netrin Receptor UNC5C (UNC5C)

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