Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody

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Catalogue No: abx034916
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Target Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14)
Clonality Monoclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified His-tagged Human USP14 protein
Isotype IgG1
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P54578 (UniProt, ExPASy)
UniProt Secondary AC B7Z4N8, J3QRZ5, Q53XY5
UniProt Entry Name UBP14_HUMAN
NCBI Accession NP_001032411.1 NP_005142.1
KEGG hsa:9097
String 9606.ENSP00000261601
Molecular Weight Calculated MW: 56.1 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14)


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