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Human Clara Cell 16kD Protein (CC16 / SCGB1A1) Protein
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Catalogue No: abx260377
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US$261.00
(Size: 10 µg)
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Datasheet SDS
Clara Cell 16kD Protein (CC16 / SCGB1A1) Protein is a recombinant cytokine. Clara Cell 16kD Protein (CC16 / SCGB1A1) which belongs to the Secretoglobin (SCGBs) superfamily, is a multifunctional protein that exerts anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. Uteroglobin is involved in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. SCGB1A1 is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia which communicate with the external environment. On top of sequestering pro-inflammatory mediators and carcinogens, Uteroglobin is implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. SCGB1A1 gene defects are associated with a susceptibility to asthma. Uteroglobin Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 15.8kDa. The SCGB1A1 is purified by proprietary chromatographic techniques.
Research Articles on Clara Cell 16kD Protein (CC16 / SCGB1A1)
| Target | Clara Cell 16kD Protein (CC16 / SCGB1A1) |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purity | > 98% (SDS-PAGE and RP-HPLC) |
| Reconstitution | Reconstitute in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage | Store lyophilized at -18°C for long term storage. It is recommended to add a carrier protein (0.1% HSA or BSA). Upon reconstitution, store at 4°C for up to 1 week. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P11684 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5F2, Q6FHH3, Q9UCM2, Q9UCM4 |
| UniProt Entry Name | UTER_HUMAN |
| KEGG | hsa:7356 |
| String | 9606.ENSP00000278282 |
| Sequence | EICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN. |
| Buffer | PBS, pH 7.4. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |