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UV Radiation Resistance-Associated Gene Protein (UVRAG) Antibody
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Catalogue No: abx030355
Price:
US$290.00
(Size: 80 µl)
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UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI (3) KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Research Articles on UV Radiation Resistance-Associated Gene Protein (UVRAG)
| Target | UV Radiation Resistance-Associated Gene Protein (UVRAG) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 666-699 amino acids from the C-terminal region of human UVRAG. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9P2Y5 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KTC1, O00392 |
| UniProt Entry Name | UVRAG_HUMAN |
| NCBI Accession | NP_003360.2 |
| String | 9606.ENSP00000348455 |
| Molecular Weight | Calculated MW: 78.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |