Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239) Antibody

VASP (pS239) Antibody is a Rabbit Polyclonal antibody against VASP (pS239). Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Target	Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239)
Clonality	Polyclonal
Target Modification	Ser239
Modification	Phosphorylation
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around S239 of human VASP.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50552 (UniProt, ExPASy)
UniProt Secondary AC	B2RBT9, Q6PIZ1, Q93035
UniProt Entry Name	VASP_HUMAN
Gene Symbol	VASP
GeneID	7408
NCBI Accession	NP_003361.1
KEGG	hsa:7408
String	9606.ENSP00000245932
Molecular Weight	Calculated MW: 40 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239)

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