Transitional Endoplasmic Reticulum ATPase (VCP) Antibody

VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

Target	Transitional Endoplasmic Reticulum ATPase (VCP)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 726-755 amino acids from the C-terminal region of human VCP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55072 (UniProt, ExPASy)
UniProt Secondary AC	B2R5T8, Q0V924, Q2TAI5, Q969G7, Q9UCD5
UniProt Entry Name	TERA_HUMAN
KEGG	hsa:7415
String	9606.ENSP00000351777
Molecular Weight	Calculated MW: 89.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Pig, Zebrafish and Xenopus VCP.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transitional Endoplasmic Reticulum ATPase (VCP)

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