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Vitamin D3 Receptor (VDR) Antibody
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Catalogue No: abx025462
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Research Articles on Vitamin D3 Receptor (VDR)
| Target | Vitamin D3 Receptor (VDR) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human VDR protein (Fragment) |
| Isotype | IgA |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11473 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5Q1, G3V1V9, Q5PSV3 |
| UniProt Entry Name | VDR_HUMAN |
| Gene Symbol | VDR |
| KEGG | hsa:7421 |
| String | 9606.ENSP00000447173 |
| Molecular Weight | Calculated MW: 48.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |